Bacteria in balance: harnessing microbiology for better dental care in India

MMDC Success

Your mouth is home to more types of bacteria than you can count, with over 700 species living in a harmonious system known as the oral microbiome. Though that might sound unhygienic, it’s perfectly normal… until the wrong kind of bacteria disrupts the natural bacterial balance. That is when Kishore Bhat, MD, can help you out.

As a medical microbiologist, Dr. Bhat focuses on understanding the effects of oral pathogens on human health—not just in the mouth. When left untreated, oral bacterial infections can drastically increase a person’s risk of developing other conditions, from rheumatoid arthritis and meningitis to pancreatic or skin cancer.

Though he had a passion for the oral microbiome, Dr. Bhat recognized that India had little infrastructure to accommodate the specialized research his field demanded. So he focused his energy on establishing the country’s first and only research center dedicated to oral microbiology at Maratha Mandal’s NGH Institute of Dental Sciences & Research Centre (MMDC).

Starting a new research facility from scratch had its challenges, and Dr. Bhat’s first need was the proper instrumentation. The Department of Microbiology, where Dr. Bhat is a professor and department chair, received over 3 tons of Instrumental Access equipment in 2019, equipping them to study these dangerous pathogens more effectively.

https://www.youtube.com/watch/?v=1MkKg2E5x7w

“Since receiving Instrumental Access equipment, we have been busy with an influx of students interested in microbiology,” says Dr. Bhat. “We are now being recognized as one of the major centers of microbiology in the country.”

The surge of interest in this rapidly-developing field is, in part, attributed to the potential unlocked by the department’s Instrumental Access shipment. Students and faculty no longer have to suspend projects due to insufficient equipment. Now, they have the tools to pursue the aggressive and pathbreaking research that Dr. Bhat envisioned when he helped establish MMDC’s microbiology department.

Dr. Bhat is currently testing his biggest idea: that greater knowledge of oral pathogens will lead to better health outcomes. Previously, progress had been stuck… but with Instrumental Access equipment in place, he and his colleagues have advanced their studies of the oral microbiome, noting many of the consequences that can result from a mouth with bacteria that goes out of balance.

Eventually, Dr. Bhat hopes that he and his team can develop a widely available rapid test for pathogens that disrupt the natural symbiosis in the oral microbiome. His goal is that such a test can be administered in a clinical setting, providing rapid diagnosis and treatment plans for issues that may have otherwise gone undetected.

If such a rapid test were to become widely available, Dr. Bhat believes that India would see a major improvement in oral and general health, as the disrupting pathogens could be treated and the oral microbiome brought back to stability.

Faculty in the Department of Microbiology at MMDC
Faculty in the Department of Microbiology at MMDC

While Dr. Bhat’s research is impressive, the impact of Instrumental Access is being felt beyond the MMDC campus. With a growing interest in oral microbiology across India, the Department of Microbiology is taking its knowledge and expertise on the road.

Dr. Bhat and colleagues are leading training sessions around the country to educate dental professionals about how the oral microbiome can affect general health. If a patient presents with gingivitis, it may not occur to a dentist that other health consequences could be lurking unseen.

Dr. Bhat’s mission is to prepare the dental workforce to think of oral disease as a potential indicator of serious general health risks and to screen for them appropriately.

As the leader of India’s only oral microbiology program, Dr. Bhat says he feels an urgent responsibility to share expertise with the broader dental community.

“The growing body of scientific research in oral microbiology has increased awareness of our field, along with the more holistic health issues that result from microbiological oral problems,” he says. “But the absence of microbiology programs in India meant that not many people were trained to address the problem.”

Today, when global pandemics have thrust science into the public consciousness, Dr. Bhat sees an opportunity to educate and empower everyone in India to take more notice of their oral health. In taking his science out of the lab and into the community, he is expanding his research’s impact many times over.

This impact is possible because a brilliant scientist has the tools he needs to follow his passion. Thousands of people will receive better dental care because Dr. Bhat is bringing his expertise to serve the public, spreading awareness of oral pathogens and how to treat them.

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EK Wahome

EK Wahome
Logistics Intern

EK Wahome started working for Seeding Labs in 2024 primarily in the Instrumental Access Program. She is currently a Junior at Tufts University studying Biochemistry and Biotechnology.

EK is passionate about making research equitable and accessible to all.

Jennifer Raymond

Jennifer Raymond
Director of Corporate Relations

Jennifer partners with corporations, universities, and nonprofit organizations to identify opportunities to repurpose surplus scientific laboratory equipment that will in turn empower talented scientists in developing countries through the Instrumental Access program.

Prior to joining Seeding Labs, Jennifer served as a Development Officer at the Harvard-Smithsonian Center for Astrophysics, where she managed relationships with donors, foundations, and corporations to advance the groundbreaking work of research scientists.

She also directed membership programs for the Boston Symphony Orchestra and alumni relations for the Heller School for Social Policy and Management at Brandeis University. Jennifer graduated from Wellesley College with a BA in French studies and a minor in philosophy.

Manisha Patel

Manisha Patel
Scientific Director

Manisha uses her scientific expertise to implement the equipment-related aspects of Seeding Labs’ programs and plays a key role in Instrumental Access.

She provides support to Instrumental Access awardees, helping them choose the instruments that best meet their research and teaching goals. She also advises the Corporate Relations team on equipment that would be useful in our awardees’ labs.

Manisha has extensive experience in managing academic research labs with knowledge spanning lab setup, compliance, and equipment training. Most recently, she oversaw labs at Harvard University.

For the past decade, Manisha directed an undergraduate internship program focused on one of her passions:  diversity and inclusion in STEM. She holds a BS in ecology from Rutgers University and an MS in ecology from the University of Vermont.

Micaela Leaska

Micalea Leaska
Programs Specialist,
Metrics & Evaluation

Micalea works with the Programs team to develop and implement metrics and evaluation tools, and to monitor the worldwide impact of Instrumental Access. She compiles and analyzes quantitative data and qualitative stories that exemplify our mantra, “talent is everywhere.”

Her prior work experience includes consulting for the World Bank, working on Water Security Assessments for Peru and Central America, and improving access to safe water in rural Ecuadorian communities with the nonprofit WaterStep.

Micalea holds a BA from Saint Michael’s College and completed her Master’s degree in Climate Change and Global Sustainability from SIT Graduate Institute, where she studied global science issues alongside scientists, stakeholders, and community members in Iceland, Tanzania, and Ecuador.

Chiudo Ehirim

Chiudo Ehirim
Instrumental Access
Consultant

After completing an Atlas Corps Fellowship with Seeding Labs, Chiudo now provides support to our Instrumental Access partners from his Rumines Ltd. office in Lagos, Nigeria. Chiudo is CEO of Rumines, an environmental technology and management consulting company.

Prior to his fellowship, Chiudo was a country manager for Nigeria with Climate Scorecard, a US-based organization that monitors how the top 25 greenhouse gas-emitting countries implement the Paris Agreement on climate change.

Chiudo earned a BS in pure and industrial chemistry from the University of Nigeria and a Master’s of Science in environmental technology and management from the University of Port Harcourt in Nigeria.

David Borman

David Borman, PhD
Communications
Director

David works to highlight the innovation and scientific successes of Instrumental Access awardees. In telling these scientists’ stories, he helps to show the global impact of the Seeding Labs mission.

Prior to joining Seeding Labs, David worked as the alumni affairs director for Brevard College in North Carolina and managed communications for Kids Center for Pediatric Therapies, a nonprofit in Louisville, Kentucky, that provides services to children with special needs.

David earned his PhD in English from the University of Miami. He holds an MA in English from the University of Louisville and a BA in English from Bellarmine University.

Christine Srivastava

Christina Viola Srivastava

Vice President of Programs

Christina is responsible for program development, planning, and implementation at Seeding Labs. 

Christina has experience as a research program evaluator and science policy analyst. She’s held roles with the consulting firm Abt Associates, Inc. and the Science and Technology Policy Institute.

Prior to entering the consulting world, Christina worked for the Boston-area nonprofits Alliance for the Prudent Use of Antibiotics and Urban Ecology Institute. She holds an undergraduate degree in biology from Swarthmore College

Rick Sherman

Rick Sherman

Vice President of Philanthropy

Rick is responsible for the fundraising activities at Seeding Labs, engaging with corporations, foundations, and individuals to increase their financial and equipment donations to the organization.

Prior to joining Seeding Labs, Rick spent 17 years working in a similar capacity at a number of science-focused organizations, including Keystone Symposia, the Carnegie Institution for Science, and the Chemical Heritage Foundation (now the Science History Institute).

Rick earned an MS in Finance from Drexel University, and a BS in Paper Science and Engineering from State University of New York College of Environmental Science and Forestry.

David Qualter

Vice President of Operations

David is responsible for global logistics at Seeding Labs, overseeing the efficient movement of lab equipment worldwide.

He joined Seeding Labs from Image Arts, a subsidiary of Hallmark Cards, where he provided logistics direction for the company with $110 million in annual sales.

He brings 20 years of supply chain management experience with in-depth knowledge of international logistics, warehouse execution, and distribution center operations.

Originally an art student at Southeastern Massachusetts University, David now uses his creative talents to develop logistics strategies that produce operational efficiencies and quality customer service.

Melissa P. Wu, PhD

Melissa P. Wu, PhD

Chief Executive Officer

Please direct speaking requests to media@seedinglabs.org


As the CEO of Seeding Labs, Dr. Melissa P. Wu connects scientists and institutions around the world to help reduce barriers to scientific discovery.

Part scientist, part engineer, and part facilitator, Melissa brings strategic insight and rigorous methodology to her work, together with a dedication to helping people.


Melissa is driven by two overarching values: that scientific research is a critical tool for improving human lives, and that research thrives and we as a community make the best discoveries when we foster diversity in perspectives, approaches, and ideas. Joining these two ideas has given her a career focus on creating opportunities for people of all backgrounds to engage in scientific research.


Prior to being named CEO of Seeding Labs in 2019,
Melissa served as Senior Vice President of Operations. She revamped Seeding Labs’ Instrumental Access program to increase its efficiency while expanding its impact.


Melissa’s previous positions at the Harvard Office for
Diversity Inclusion and Community Partnership and the BioBuilder Educational Foundation helped spread scientific knowledge to students nationwide.

She is proud to have mentored many students through
programs at the Journal of Emerging Investigators, Harvard, Boston Children’s Hospital, and MIT.

Melissa earned a PhD in Cellular and Developmental
Biology from Harvard University and holds an SB in Biology from the Massachusetts Institute of Technology.